tirzepatide surpass-4 Efficacy and safety of monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono): a double-blind, multicentre, randomised, phase 3 trial Tirzepatide versus Semaglutide Once Weekly

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Under pathological conditions, however, excessive EAT accumulation releases pro-inflammatory adipokines via vasocrine or paracrine pathways, exacerbating cardiac damage (99), a phenomenon particularly prevalent in patients with coronary artery disease and diabetes mellitus (95)