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Beyond blood pressure control, clonidine has diverse off-label applications, including management of attention-deficit/hyperactivity disorder (ADHD), Tourette syndromeassociated tics, and autonomic hyperactivity during opioid, alcohol, and nicotine withdrawal

The result is a situation where desire and performance become decoupled

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doi: 10.1016/j.jchemneu.2015.07.004 42 GhirardiniEWadleSLAugustinVBeckerJBrillSHammerichJet al