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Both #semaglutide and #tirzepatide demonstrate significant reductions in HF hospitalization and mortalityyet the lack of incremental benefit with tirzepatide over semaglutide raises key questions about mechanism of action, dose-response, and patient selection
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HLH across Speciality collaboration, UK
[1] Local anaesthetics work by blocking sodium channels in nerve fibres, preventing the transmission of pain signals, and this mechanism does not interfere with GLP-1 receptor activity or glucose metabolism
