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The implication for clinical practice is that restoring youthful MOTS-c signaling might be a mechanistically legitimate target for longevity intervention
Studies show it does not raise cortisol or prolactin in a significant way, reducing side effects such as water retention
This action accelerates wound closure and reinforces barrier function by up-regulating collagen synthesis genes and down-regulating pro-inflammatory cytokines like TNF-
Additionally, eryptosis offers a higher reproducibility, easier quality control, better data precision, and the opportunity to identify changes in eryptosis signaling pathways at the suberyptotic concentrations of nanomaterials
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