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Protecting Sleep Architecture The National Sleep Foundation recommends finishing vigorous exercise at least 3 hours before bedtime [14]

Four months after cessation of LC supplementation, plasma TMAO reached a pre-supplementation concentration, which was stable for the following 8 months [60]

All direct vasodilators produce a sympathetic response including an increase in heart rate, stroke volume, and cardiac output, and a marked increase in plasma renin activity, which, in turn, leads to increased sodium and water retention

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