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However, to simplify research interpretation in the field, PS externalization may be considered a decent marker of eryptosis, indicating the occurrence of this RCD even in aged cells expressing senescence-associated markers
Moreover, topiramate, an anti-epileptic drug that provides neuroprotection by preventing glutamate toxicity, has antidiabetic and beta-cell cytoprotective effects [129] and long-lasting remission was observed in a T1D patient after treatment with topiramate for generalized seizures [130]
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