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Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications increasingly prescribed for type 2 diabetes management and, more recently, for weight management in adults with obesity
The resin was packed into a glass column and washed with 20 column volumes of 20 mM HEPES pH 7.4, 100mM NaCl, 2mM MgCl 2 , 5mM CaCl 2 , 1M peptide, 0.01% (w/v) LMNG and 0.0006% (w/v) CHS followed by elution with buffer containing 5mM EGTA and 0.1mg/ml FLAG peptide
Participants (18 years) with inadequately controlled type 2 diabetes (HbA1c 80-100%) with metformin and with or without sulfonylurea were randomly assigned (1:1) by an interactive web-response system to 20 mg or 10 mg once-weekly semaglutide
Geng N, Shi BJ, Li SL, Zhong ZY, Li YC, Xua WL, et al
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