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Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients

Side effects, drug interactions, dosing, storage, and pregnancy and

Quality Assurance and Manufacturing Standards The 10mL vial sold here is produced in a US facility that operates under cGMP-aligned quality controls

You can use sterile water only if you intend to use the entire contents of the vial immediately after reconstitution