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In this study, we report that a select set of metabolites, such as phosphoenol pyruvate (PEP), glutathione (GSH), 2-hydroxyglutarate (2-HG), and NAD + , display significant differences between the healthy and diseased motor cortex with TDP-43 pathology at a symptomatic stage
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In addition, leaky gut can carry intestinal-resident bacteria to tumors via the bloodstream, which can positively or negatively affect immune responses (Ludgate et al
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