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As WD is an autosomal recessive disorder, an individual must inherit two copies of the mutated ATP7B gene, one from each parent, both of whom are usually carriers (see Figure 1)[8]
GLP-1 treatment can exert the direct action on reversing vascular remodeling by downregulating MMP1 expression via alleviating the ERK1/2/NF-B pathway in Ang II-induced rat aortic VSMCs [130]
Presented for research literature review only Ramage PI et al
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