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In contrast, CHMP1A haploinsufficiency greatly exacerbated FA- or cisplatin-induced AKI by promoting ferroptosis through iron accumulation [177]
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In PCOS, IR and HA contribute to iron overload by downregulating Hepc expression, thereby diminishing its inhibition on FPN
reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)
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