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The standard cagrilintide monotherapy titration follows this schedule: 0.25 mg weekly for weeks 1-4, then 0.5 mg for weeks 5-8, then 1.0 mg for weeks 9-12, then 1.7 mg for weeks 13-16, and finally 2.4 mg for week 17 onward as the maintenance dose
Zhu D, Shen Z, Liu J, Chen J, Liu Y, Hu C, Li Z, Li Y
This result suggested they might be recognizing nontarget features, such as the GGS linker between lysozyme and RNAP, rather than authentic substrate residues
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