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Eli Lilly press release, December 11, 2025 TRIUMPH-4 Phase 3 results in obesity + osteoarthritis
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Expected milestones during therapy: Baseline assessment and initial labs Early symptom change (26 weeks) Objective lab improvement (612 weeks) Dose optimization and protocol refinement (3 months) Long-term maintenance or tapering plans (612 months) Expectations While most patients experience progressive symptom relief, some begin to notice changes within 2 to 6 weeks, with measurable reduction in inflammation present by 8 to 12 weeks
It is for this reason that we cant cut out fiber for methane SIBO and why diets like Low FODMAP can cause further issues if not properly adapted
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