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Quick Answer: GLP-1 receptor agonists improve fatty liver disease by reducing liver fat content, improving liver enzymes, and achieving NASH resolution in clinical trials, primarily through weight loss and enhanced insulin sensitivity
The combination eliminates the need for two separate injections, reduces total injection volume, and ensures consistent dosing ratios optimized for synergistic effects
To achieve weight loss efficacy with oral GLP-1 drugs, higher concentrations are needed as well as absorption enhancers
They also act on appetite centres in the brain, reducing hunger signals and food cravings
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