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Moreover, studies have indicated that the interaction between FOXOs and P53 can modulate aging in yeast and invertebrates (Chen et al., 2022)

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Future studies including both male and female offspring, with adequate power to evaluate sex-by-treatment interactions, are needed to determine whether LipRSV produces sex-specific behavioral and biochemical effects

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These results established cagrilintide as a clinically meaningful agent in its own right, while also confirming that its mechanism was distinct enough from existing therapies to warrant combination investigation

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Sahay A, Kale A, Joshi S

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