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This timing was chosen based on previous research, which suggests that L-carnitine supplementation can influence performance when taken 6090 min before exercise, allowing sufficient time for absorption and metabolism
BMC Med 20 , 272 (2022)
A few case reports also describe muscle breakdown with kidney strain and serious kidney events
If results are promising, the programme moves to Phase 3: larger, global, randomised trials involving, dependent on the indication hundreds to sometimes even thousands of participants, designed to confirm efficacy and build a robust safety profile
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