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Some reported or potential side effects include nausea, facial flushing, decreased appetite, headache, fatigue or drowsiness, yawning/stretching, injection-site irritation, and changes in arousal or spontaneous erections
In adults, neurologic symptoms of biotin deficiency include depression, lethargy, hallucinations, and numbness and tingling of the extremities (35)
These mixed responses cannot be generalized, but the fact that a subset experience real improvement makes this an important signal to investigate
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