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Following the release of a drug, the FAERS database collects adverse events reports from providers and patients that are witnessed in-market (i.e., in the real world practice of medicine rather than during a clinical trial or drug testing process)
At the same time, overall spending on GLP-1 drugs has grown substantially, with national pharmacy spend rising more than 500 % from 2018 to 2023, underscoring the economic impact on payers and employers alike
Acknowledgements The authors thank Marie Kim Wium-Andersen and Ida Kim Wium-Andersen for valuable sparring in relation to the analysis plan
[57] Furthermore, semaglutide improves the brain's sensitivity to leptin, a hormone produced by fat cells that signals satiety to the brain
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