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The broader implication may be even more important than any single medication
One of these is the incretin hormone, glucagon-like peptide-1 (GLP-1), which plays an important role in the maintenance of normal glucose homeostasis, and DPP-4 has been shown to be the key enzyme regulating its biological activity
25,26 GIP is known to bind to the GLP-1R/GIPR heterodimer, a member of the family of G protein-coupled receptors
This medication is not recommended for people with preexisting conditions, such as glaucoma, hyperthyroidism, or a history of extensive cardiovascular disease
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