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Tesamorelin + Ipamorelin is the most widely studied and safest stack for growth hormone optimization
A randomized controlled trial published in the New England Journal of Medicine demonstrated that tesamorelin significantly reduced visceral adipose tissue in patients with abdominal fat accumulation (Falutz et al., 2007)
It is one of the most heavily researched peptides in preclinical literature, with over 100 published animal studies and a sharp rise in PubMed entries from roughly 45 in 2020 to more than 180 in 2025
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(2011a)
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