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This vitamin b12 deficiency skin problems tend to cause darkening of the skin, patchy, especially on the hands, feet, and joints
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doi: 10.1016/j.tics.2011.03.002 73 BelcherAMLejuezCWMoellerFGVolkowNDFerrS
And Hua-song Liu and some of the other folks at that time at MIT did
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