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Nagahisa T, Saisho Y

Inflammation, Oxidative Balance, and Radical Chemistry A series of reports propose that GHK and GHK-Cu may interact with oxidative pathways by diminishing selected reactive species in cellular systems and by moderating lipid peroxidation chemistry linked to free iron

This is non-linear pharmacokinetics (PK), and it's the reason small dose changes can produce outsized exposure changes

Concurrently, it interferes with noncanonical pathways, including the Wnt/-catenin and NF-B pathways, thereby maintaining epithelial cell polarity and structural integrity and suppressing EMT and ECM deposition (35)