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conducted target trial emulations comparing dual GLP-1/GIP agonists to GLP-1 monotherapy in patients with type 2 diabetes, finding that dual agonists were linked to numerically lower risks of MALOs, although confidence intervals overlapped, suggesting that extended observation period and larger patient cohorts may be needed to definitively establish comparative effectiveness [61]
Xiang J, Qin L, Zhong J, Xia N, Liang Y
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Patients on GLP-1 medications experience fat loss to varying degrees, and because cheek volume depends on both fat and collagen, that loss can make the face look flatter or more deflated faster than typical aging alone, says New York dermatologist Jane Yoo, MD
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