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Medical Supervision: Essential for safety and effectiveness

We speculate that ferroptosis contributes to SARS-CoV-2 infection-related PD in light of the possible link between ferroptosis and neurological abnormalities in COVID-19 patients

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While estimands do not solve all problems of trial design and interpretation, this new concept will enable trials to be designed more appropriately to obtain relevant information to address the clinical question(s) of interest