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Later, structures of the AR LBD complexed with its physiological agonists DHT (PDB: 1I37 or 2AMA) and testosterone (PDB: 2AM9) were solved (Figure 3B) 67,68

Furthermore, its weight loss effect, achieved by reducing fat accumulation, preserves an appropriate amount of muscle mass during weight reduction, preventing muscle atrophy due to nutritional deficiencies and maintaining normal physiological functions and bodily resistance

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[1] [2] These medications work by mimicking the action of naturally occurring incretin hormones that the body produces in response to food intake