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Retatrutide is an investigational triple-receptor medication being studied for GIP, GLP-1, and glucagon receptor activity
However, this would represent an off-label, experimental approach that falls well outside current NICE guidance or standard NHS practice, and should only ever be considered within a formal clinical trial or with robust multidisciplinary oversight, documented informed consent, and a clear monitoring plan
mostly gone by weeks 24 Diarrhea: ~3 days per episode Constipation: average 47 days
The side effects are usually mild to moderate and worst while the dose is increasing
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