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These cellular stressors activate inflammatory cascades involving Kupffer cells, recruited macrophages, and other immune cells, perpetuating hepatic inflammation through secretion of inflammatory mediators and cellular damage signals [7]
According to the National Institutes of Health Office of Dietary Supplements, an estimated 6% of adults under 60 in the United States are B12 deficient, with the prevalence rising to nearly 20% in adults over 60
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