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In high-fat-diet rodent models, changes in body mass or adipose-tissue measurements may reflect the experimental metabolic endpoint being studied, but safety interpretation is stronger when paired with food intake, body composition, activity, general observations, serum chemistry, hematology, organ weights, and histopathology
Individuals at risk of deficiency, such as vegetarians, vegans, older adults, or those with digestive disorders, may benefit from Vitamin B12 injections
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Doctors keep an eye out for allergic reactions or heart problems
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