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Studies have shown that the peptide demonstrates approximately 40% oral bioavailability in animal models and exhibits rapid metabolism with a serum half-life of approximately 4 minutes, though its metabolic effects persist significantly longer due to downstream cellular activation
Furthermore, western blot was used to analyze the protein levels of representative senescent markers, including p16, p21, and p53
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency
A 30-day follow-up found no significant changes in selected liver and kidney laboratory markers, but the group was small and the duration was insufficient to define long-term safety
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