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Loading phase: Some protocols include a short loading period, while others skip it and still reach similar muscle creatine levels over time

A meta-analysis revealed that supplemental intake of 4,000 mg L-carnitine increases serum albumin levels and ameliorates serum ammonia levels in patients with hepatic encephalopathy (14)

This is supported by other studies that showed a protective effect of L-carnitine against ammonia-evoked encephalopathy in cirrhotic patients, with ALC administration improving neurological symptoms and plasmatic parameters in cirrhotic patients with hepatic coma [6067]