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Testosterone replacement therapy (TRT for short) may help your immune system in the following ways: Balance TH1 and TH2 (10) immune responses Lower the autoimmune process and autoimmune attack on the thyroid gland (and, in some cases, suppress it) (11) Enhance weight loss (a great benefit for many patients with Hashimotos thyroiditis) Increase libido and sex drive (12) How do you know if you are a potential candidate for using testosterone therapy to treat Hashimotos