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It functions as an electron carrier in cellular respiration and as a substrate for sirtuins (longevity proteins) and PARP enzymes (DNA repair proteins)
doi: 10.1038/s41419-021-03452-x 82 PeiXLiuJWeiYZhuYLiYWangQet al
Glutathione is also widely used in cosmetic and skincare products for skin brightening and reducing hyperpigmentation, thanks to its ability to inhibit melanin production
Months 3-6: Approaching the Maintenance Phase What the trials documented: By around month four (week 17), the REDEFINE protocol reached the 2.4 mg maintenance dose, and weight loss continued to accrue beyond that point through the 68-week primary endpoint (Aronne et al., 2025)
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