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Further investigation of the intestinal microbiome metabolism of orally supplemented l-carnitine in patients with IEMs is needed to answer the following questions raised by this study: (1) Does chronic oral l-carnitine supplementation increase the risk of atherosclerosis in individuals with organic acidemias

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose