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Semaglutides cardiovascular benefit data (the SELECT trial, 2023) remains a distinct advantage for high-risk patients, and this consideration may guide some providers to recommend semaglutide even for patients currently on tirzepatide
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Semaglutide is the active ingredient in some of the most recognized drugs on the market today Ozempic (injection), Wegovy (injection and now pill), and Rybelsus (pill for diabetes in adults)
Together with pharmacological studies, the results reveal the conserved binding mode of peptidic agonists and provide molecular details of agonist recognition underlying receptor subtype selectivity
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