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It occurs endogenously in humans, where it has been identified in the hypothalamus, the limbic system, the pituitary, and even the gastrointestinal tract
Therefore, given the rarity of suicidal or self-harming behaviors, the limited sample size of the RCT, and the inherent limitations of retrospective studies, comprehensive research with long-term follow-up and rigorous mental health assessments is needed to clarify the potential risks and benefits
If the plasma bound-form glutathione were to be converted to the reduced form before passing through the cell membrane, it would have to be transported into hepatocytes containing extremely higher concentrations of the same compound
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