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In a randomized trial mentioned earlier, participants who took a combination of glutathione and L-cystine orally for 12 weeks saw a significant reduction in the size of facial dark spots compared to placebo
3) leading to the discovery of PLGA as a material with customizable properties through varying the lactic-to-glycolic acid ratio 105,106
Studies have continually demonstrated a strong link between a dietary reliance on cyanogenic cassava coupled with general malnutrition, however, these risk factors are present in many regions of sub-Saharan Africa where konzo does not occur 5,24,25
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