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this occurs because there is not enough vitamin B12 in the diet or poor absorption Pernicious anaemiaa type of megaloblastic, autoimmune anaemia caused by a lack of intrinsic factor (a protein in the stomach that allows the body to absorb vitamin B12) so that vitamin B12 is not absorbed [8] Fatigue, weakness, low energy Frequent bleeding or bruising Shortness of breath Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Digestive issues Heart palpitations Dementia Depression Seizures Toxicity How do you measure Vitamin B12