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3A shows distinct cellular clusters across the experimental groups, including endothelial cells, epithelial cells, fibroblasts, lymph endothelial cells, macrophages, nerve cells, perichondrial cells, smooth muscle cells, and T cells
Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome
PMID: 15616239
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