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The crystallization of HpTpx red and its complexes, HpTpx_C R A: Metro * (co-crystal structure of HpTpx C94A mutant with Metro in its amine form (*)) and HpTpx_C R A: Metro-P3 * (co-crystal structure of HpTpx C94A mutant with Metro-P3 in its amine form (*)), was performed using the sitting drop vapour diffusion method at 20 C

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We thank the staff of the Rheumatology and Immunology Laboratory and Medical Scientific Research Center in Peking Union Medical College Hospital (PUMCH) for providing experimental equipment