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Comprehensive Benefits with Sustained Efficacy Over 52 Weeks The approval of ecnoglutide injection is supported by its Phase III EECOH-1 and EECOH-2 clinical trials, which evaluated the efficacy and safety of the drug in Chinese participants with T2DM as monotherapy and in combination with metformin, respectively
The exact biological mechanism by which GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists like tirzepatide might induce dysesthesia or allodynia is not fully understood
Its direct CNS-targeted mechanism sets it apart from peptides that influence peripheral pathways, making it particularly valuable for investigations centered on neurological and behavioral regulation
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