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GLP-1 Therapy Options for Patients Without a Gallbladder Both oral and injectable semaglutide can be used post-cholecystectomy, but many patients report better tolerance with injections because they bypass the altered digestive environment in the stomach and small intestine

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Severe gastrointestinal disease: Caution is advised in patients with conditions such as gastroparesis or severe inflammatory bowel disease, as GLP-1 receptor agonism slows gastric emptying

Ozempic Since both Rybelsus and Ozempic are semaglutide medications, they tend to have similar side effects