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395 Multifunctional nanocarriers coloaded with a STING agonist and PD-L1 siRNA not only activate the STING pathway to boost innate immunity but also inhibit PD-L1 expression, enabling potent immune activation and broad-spectrum inhibition in cold tumors
Increased cellular catabolism, heightened endogenous purine synthesis, and a diet rich in purines can elevate urate levels
at 100% vVO 2 max interspersed with 1 min
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