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The result is a 16-amino acid peptide that stimulates lipolysis through beta-3 adrenergic receptors on fat cells, without triggering IGF-1 elevation, insulin resistance, or the growth-promoting effects that make full HGH problematic for long-term metabolic use
Continuation criteria vary by medication: for Wegovy, evaluate at 20 weeks with a target of 5% weight loss
7 , 339357 (2008) Runge, S., Thgersen, H., Madsen, K., Lau, J
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