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Thus, the principal benefit of probiotics in HPV management likely resides in their capacity to restore and reinforce a protective vaginal microbiota, an effect that may outweigh specific treatment variables such as duration or route of administration (480)

H., Ghesquire, B., McVicar, D

IFN- can also activate CD8+ T cells and natural killer (NK) cells to produce perforin and granzymes, inducing programmed cell death of the infected target cells and destruction of the intracellular pathogen

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