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A very large fraction of published binding constants for melanocortin ligands, including those for cyclic analogues, peptidomimetics and candidate subtype-selective compounds, are reported as inhibition of I-NDP-alpha-MSH binding to membranes from cell lines stably expressing a single human receptor subtype
Mortazavi S, Vadoud S, Moghimi H
However, a discovery that bacterial pore-forming toxins can induce necroptosis (a programmed necrosis) also in red blood cells (RBCs) is striking and could eventually lead to a re-conception of erythrocytes as entities between life and death [25]
Medically reviewed by Sanjeda Chowdhury, Superintendent Pharmacist + Independent Prescriber Reviewed on Jul 15, 2026
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