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Important safety considerations include risk of pancreatitis (treatment should be discontinued if suspected), gallbladder disease, and potential worsening of diabetic retinopathy in patients with pre-existing retinopathy who experience rapid improvement in glucose control (particularly with semaglutide)
However, retatrutide has not yet received marketing authorisation from the MHRA or EMA, meaning it is not currently available as a licensed medicine in the UK
As a lot of risk factors of hair loss, like smoking, stress or UV radiation exposure are associated to the damaging effect of reactive oxygen species (ROS) [20] [21], a compromised antioxidant-defence system, due to selenium deficiency, will likely worsen the negative effects of these risk factors
doi:10.1177/1932296819870849
