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no melanoma events in over 1,000 treated patients across surveillance periods No serious drug-related events : No consistent serious adverse events attributed to afamelanotide in pivotal trials Melanotan-2 Safety Profile# Melanotan-2 carries substantially more safety concerns: Common effects : Nausea in approximately 38% of injections (severe in approximately 15%)

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Shoffner J, Hyams L, Langley GN, Cossette S, Mylacraine L, Dale J, et al

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