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The most commonly reported effects are mild and temporary slight redness, tingling, or dryness at the application site, especially when first starting or stepping up to a higher strength
Severe or persistent side effects warrant discontinuation and medical evaluation
Liraglutide has a relatively short half-life of around 13 hours, which means the medication level in your bloodstream drops by half in about half a day
Native human GLP-1 has a roughly two-minute half-life, so an exendin-4-based long-acting analog was the practical entry point for the drug class
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