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In 1926, after Minot and Murphys success with liver therapy for pernicious anemia, William Bosworth Castle (1897-1990), then an assistant resident at the Thorndike Memorial Laboratory of Boston City Hospital (which had recently come under the direction of Minot as successor to Francis Peabody), decided to pursue his belief that gastric achlorhydria (achylia gastrica) was etiologically linked to pernicious anemia (139)
That could leave thousands of patients without access to low-cost alternatives a gap Novo says it is prepared to fill
If the Cyp2e1 effect from the Yale study translates to humans, the same number of drinks produces higher blood alcohol than it did before starting treatment
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