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10.1038/nature12721 33 GaoY.NananR.MaciaL.TanJ.SominskyL.QuinnT
While dietary weight loss strategies typically cause some loss of lean muscle, GLP-1 and GIP/GLP-1 receptor agonists are associated with significant loss of lean mass ranging from 1545% of total weight loss,260 varying by agent
Women aged 25-45 with BMIs between 25-28 kg/m were randomly assigned to one of two groups: [5] Supresa group: 176.5 mg of standardized saffron extract daily (split into two doses) Placebo group: Identical-looking capsules with no active ingredients A key point that differentiates this study from many weight loss trials is that participants were not placed on any caloric restrictions
2010 December;11(6): 508513
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